The chirality of the compound - DASH

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The chirality of the compound

R

S

E

Z

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Step-by-Step Solution Step 1: Identify the Chiral Center Locate the carbon atom which is attached to four different substituents. This carbon is the center of chirality. Step 2: Assign Priorities to the Substituents Use the Cahn–Ingold–Prelog (CIP) rules to assign priorities (1, 2, 3, 4) to each substituent based on the atomic numbers of the atoms directly bonded to the chiral center. Highest priority (1): The substituent with the highest atomic number on the directly bonded atom. Lowest priority (4): The substituent with the lowest atomic number on the directly bonded atom. Step 3: Orient the Molecule so that the Lowest Priority Group is Directed Away Visualize (or redraw) the molecule so that the substituent with the lowest priority (4) is positioned behind (into the plane). Step 4: Determine the Direction of Priority Sequence Look at the arrangement of priority 1 → 2 → 3 while the lowest priority group (4) is behind. If the rotation from 1 → 2 → 3 is clockwise, the configuration is R. If it is counterclockwise, the configuration is S. Step 5: Conclude the Configuration Upon applying the CIP rules and viewing the molecule, the sequence 1 → 2 → 3 proceeds in a clockwise manner, confirming that the correct configuration of the chiral center is R. Answer: R

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